Missionaries of the Precious Blood are not defined by what they do, but rather the spirituality which informs their ministries. Missionaries of the Precious Blood believe in the power of the blood of Jesus, shed for all, to heal a broken world.

Missionaries of the Precious Blood serve where there is a need: in parishes, schools, health care institutions, retreat houses, in urban and rural areas. Missionaries of the Precious Blood are called to walk with those they serve in their times of joy and sorrow. They are especially called to minister to those people who live on the margins of society. Precious Blood spirituality calls Missionaries to encourage reconciliation in the communities they serve.